Laxative Usage For Managing Chronic Constipation
The most prevalent type of constipation is known by the descriptor “idiopathic” or “functional”. The meaning of these words imply that the root cause is not known, but the condition is clearly diagnosed from its symptomatic effects. Often the first treatment is dietary fiber infusion. In the event that this is not effective (which is approximately 70% of cases), patients can try out medical laxatives.
The general consensus among physicians and researchers is that laxative constipation treatments is safe and well-tolerated. But given that some patients must take them over long periods of time, doubts have come up about both efficacy and long term, unintended consequences. A consequence of these doubts have been the appearance of what seems to be misconceptions concerning laxative usage.
Roughly the myths concerning laxatives can be divided into three types. First, some believe that laxatives cause nerve damage to the colon. Second, some believe that cancer can be caused by laxatives. Third, some believe in the concept of laxative “intolerance” and “rebound” effects, resulting in worsening constipation after medication.
On the topic of the first misconception, reports about nerve damage came up first in a survey of patients who were using laxative constipation treatments. Colonoscopy showed discoloration in their intestinal lining, and some were diagnosed with damage to the nerves. But the correlative link was never made definitive. Many criticized the findings by pointing out in general patients with constipation had more chance of nerve damage, regardless of laxative use or not.
On the topic of the second, people reported a connection from laxatives to cancer by looking at animal experimentation. Rodents which were given very high doses of laxatives showed more DNA damage and thus propensity toward cancer. Yet the studies used extremely high concentrations of drugs that are never seen in humans. Likewise, studies with such high concentrations of aspartame and artificial sweeteners show a link between consumption and cancer that are rarely realized in epidemiological surveys.
With respect to the third, informal evidence from self-reporting patients suggested the idea of rebound and intolerance to laxatives. Well-controlled studies, on the other hand, showed that in patients who had used medication for as long as 30 years still benefited from consistent usage. Animal studies suggested also a lack of the intolerance effect.
Laxatives seem to be a helpful part of the treatment regimen to combat constipation. The reports of these three kinds of side effects needs to evaluated against case studies which show the opposite: that long term side-effects are not a given.
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